The South Tampa intersection of Euclid and MacDill avenues is closed while crews repair a water main break.
Euclid, between MacDill and Bayshore Boulevard, is open to only local traffic, officials said.
Eastbound access from Himes Avenue to the northbound ramp of the Selmon Expressway is available. Other than local traffic, those exiting the southbound Selmon Expressway will need to turn right toward Himes.
The intersection is expected to reopen to traffic about 3:30 p.m. Friday, officials said.
Commuters can use El Prado or Bayshore boulevards as alternatives.